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Following the fourth cycle, a single test session was conducted using a dose of 0.003 mg/kg semaglutide, included in the acute dose response curve to evaluate whether a lower dose might fall below the threshold required to alter alcohol discrimination (Fig

Each compound was also incubated in the absence of pancreatin (8.3 L of the oligomer stock solution was diluted with 190 L of TRIS 10 mM pH 7.5)